Bacterial overgrowth treatment
A systematic review of diagnostic tests for small intestinal bacterial overgrowth.
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Khoshini R, Dai SC, Lezcano S, Pimentel M. Review article: small intestinal bacterial overgrowth-prevalence, clinical features, current and developing diagnostic tests, and treatment. Fatigue and abdominal bloating predict small intestinal bacterial overgrowth (SIBO) in patients with ulcerative colitis (UC).
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Patricio Ibanez MP, Melmed GY, Ippoliti A, Targan SR, Vasiliauskas EA. Patients with chronic renal failure have abnormal small intestinal motility and a high prevalence of small intestinal bacterial overgrowth. Small intestinal bacterial overgrowth in patients with chronic pancreatitis. Signoretti M, Stigliano S, Valente R, et al. A link between irritable bowel syndrome and fibromyalgia may be related to findings on lactulose breath testing. Pimentel M, Wallace D, Hallegua D, et al. Brain-gut-microbiota axis in Parkinson's disease. Small intestinal bacterial overgrowth in gastroparesis. Intestinal methane production in obese individuals is associated with a higher body mass index. Small intestinal motility disturbances and bacterial overgrowth in patients with liver cirrhosis and portal hypertension. Gunnarsdottir SA, Sadik R, Shev S, et al. Small-intestinal bacterial overgrowth in patients with liver cirrhosis, diagnosed with glucose H2 or CH4 breath tests. Molecular assessment of differences in the duodenal microbiome in subjects with irritable bowel syndrome. Giamarellos-Bourboulis E, Tang J, Pyleris E, et al. Small intestinal bacterial overgrowth in rosacea: clinical effectiveness of its eradication. The place of antibiotics in management of irritable bowel syndrome: a systematic review and meta-analysis. Abnormal intestinal motor patterns explain enteric colonization with gram-negative bacilli in late radiation enteropathy. The prevalence of overgrowth by aerobic bacteria in the small intestine by small bowel culture: relationship with irritable bowel syndrome. Pyleris E, Giamarellos-Bourboulis EJ, Tzivras D, et al. This study showed that abscent phase III MMCs is a risk factor for bacterial overgrowth. Dysmotility and proton pump inhibitor use are independent risk factors for small intestinal bacterial and/or fungal overgrowth. Jacobs C, Coss Adame E, Attaluri A, et al. Irritable bowel syndrome and small intestinal bacterial overgrowth. Small intestinal bacterial overgrowth syndrome. Risk factors for small bowel bacterial overgrowth and diagnostic yield of duodenal aspirates in children with intestinal failure: a retrospective review.
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Gutierrez IM, Kang KH, Calvert CE, et al. Gastrointestinal bacterial overgrowth: pathogenesis and clinical significance. Papers of particular interest, published recently, have been highlighted as: In this review, we will discuss the current evidence for the diagnosis and treatment of SIBO, which includes (1) elimination/modification of the underlying causes, (2) induction of remission (antibiotics and elemental diet), and (3) maintenance of remission (promotility drugs, dietary modifications, repeat or cyclical antibiotics). Clearly, there is a strong need to develop a systematic approach for the management of SIBO and to perform multicenter clinical trials for the treatment of SIBO. Treatment of SIBO remains empirical generally, broad spectrum antibiotics are recommended for 2 weeks (amoxicillin, rifaximin, ciprofloxacin, etc.) but evidence for their use is fair. However, there is a lack of standardization of these tests and their interpretation. Several tests have been proposed, including the glucose breath test, lactulose breath test, small intestinal aspiration and culture, and others. Although known for many decades, there is a lack of consensus and clarity regarding the natural history and methods for its diagnosis. Small intestinal bacterial overgrowth (SIBO) is characterized by an excessive amount of bacteria in the small intestine and a constellation of symptoms that include bloating, pain, gas, and diarrhea.